The term "humidifying" the respiratory tract has become accepted with reference to the additional benefit derived from nebuliser therapy. In fact, the saline mist does a great deal more on the surface of the lungs. Depending on the concentration of ions that reach the airway surface layer (ASL), its physical properties change1. Clinically, these changed properties result in secretolysis secretolysis
Production of thin fluid mucus (secretolysis) for its eased removal.
and easier clearance, for example2. Moreover, it has also been shown that the spectrum of exhaled particles changes after saline solution has been inhaled. The authors of this study suggest that this may be a chance to reduce the spread of respiratory tract infections3.

Watanabe et al. 2007; J Colloid Interface Sci 307(1): 71

2  Inhalation News October 2008

Edwards et al. 2004; Proc Natl Acad Sci U S A 101(50): 17383


Reasearch findings