How much medication should be left in the eRapid Medication Reservoir at the end of the treatment?

Following treatment only about 1 mL (1/5 teaspoon) of medication should be remaining in the Medication Reservoir. If more than 1 mL remains (see image), put the Medication Cap back on and restart the treatment. Following treatment, clean the Aerosol Head.1

eRapid Drug Reservoir 

1 eRapid Nebulizer System Instructions for Use. 178D1009. Rev B 10/12

Isn't the eRapid Nebulizer System more efficient than a jet nebulizer?

The performance of the eRapid Nebulizer System is designed to match the aerosol delivery of the LC PLUS jet nebulizer but with significantly faster delivery times. The eRapid nebulizer was designed to retain approximately 1 mL of drug which is similar to residual volume left in traditional jet nebulizers.

How do I clean my VORTEX® Holding Chamber? 

  • Soak parts and mask for 15 minutes in luke warm water with liquid detergent.
  • Alternatively, place Vortex® parts in top shelf of dishwasher. Hand wash mask separately.

Refer to the PARI VORTEX® Instructions for Use for more information.

How do I know when to replace my PARI Reusable Nebulizer?

PARI Reusable Nebulizers are designed to last 6 months from first use with proper cleaning.

Advantages of Replacing your Nebulizer Cup:

  • Consistent medication delivery to the lungs
  • Fast and efficient treatments
  • Bacterial contamination can be reduced*

*Lester, Mary K. Nebulizer Use and maintenance by Cystic Fibrosis Patients; A Survey Study, Respiratory Care 2004;49(12) 1504-1508.

MEDICARE guidelines (U.S.) allow for a replacement reusable nebulizer every 6 months. It is important to keep an extra nebulizer on hand at all times.

How long will the eRapid Handset last?

The eRapid Handset may last up to six months with moderate usage, proper cleaning, disinfection and use of the Easycare cleaning aide. Duration of use may decrease when using multiple drugs or if the handset is not properly cared for according to the eRapid Nebulizer System IFU. Performance over repeated use can deteriorate quickly depending on which drugs are used, how many per day, the patient's cleaning/disinfection habits, etc. Even with proper care, it is expected that nebulization time will gradually increase over the lifetime of the handset.

How often do I change my filter on my PARI compressor?

All PARI compressors include a long lasting filter designed to last up to 500 hours of use. Your compressor air filter is bright white when new. With use, the filter will slowly turn grey, indicating the need for replacement. The filter must be replaced immediately if it gets wet or becomes clogged. A good rule to follow is to replace your filter every 6 months – at the same time as your PARI reusable nebulizer.

My nebulizer cup is not producing mist, what should I do?

If your nebulizer cup is not producing mist, first make sure that you are using a PARI Reusable Nebulizer. Refer to your instructions for use if you are not sure. Once you have confirmed that you have a PARI Reusable Nebulizer, boil the cup (except for tubing and mask) for 5 minutes. Refer to your instructions for use for further cleaning/disinfecting procedures.

My treatments are taking longer than they did before, is this expected?

PARI nebulizers are known for consistent medication delivery and short treatment times. If your treatments are taking longer than they used to, first properly clean and disinfect your nebulizer according to the instructions for use. If your nebulizer nozzle is clogged, please replace immediately.

It is also important for you to replace your nebulizer cup every 6 months for fast and consistent treatments. If it has been longer than 6 months since you last received a new PARI reusable nebulizer, contact your physician, pharmacy, or medical equipment company to order a new one.

What attachment or mask should I use to deliver aerosols to babies and young children?

Patients and Caregivers have a few options for delivery of aerosol to young children. PARI BABY™ masks were designed especially for younger patients ages 3 and under. PARI BABY™ masks includes an elbow piece and a soft, tight fitting silicone mask that fits comfortably over the nose and mouth of the patient. This allows the caregiver to give a treatment in almost any position, such as lying down in a crib or stroller, standing, or sitting on a lap.

Children ages 3 and up can use the safe and child-friendly Bubbles the Fish™ II pediatric mask that efficiently delivers medication to the lungs while reducing facial and ocular deposition.

What is the best way to clean and disinfect my PARI Reusable Nebulizer?


  • After every treatment thoroughly rinse the nebulizer to remove medication.
  • Hand-wash with warm water and dish soap, then rinse thoroughly
  • Alternatively, wash in the dishwasher using a dishwasher basket on the top rack.


  • Clean nebulizer as indicated above.
  • For low level disinfection every other treatment day:
    • Mix a solution of 1 part distilled white vinegar and 3 parts warm tap water in a clean bowl. Soak the nebulizer parts (except the tubing and mask) for 60 minutes, then rinse thoroughly.
    • Alternatively, mix a solution using Control III® Nebulizer Disinfectant and follow manufacturer’s instructions. Rinse thoroughly.
  • Alternatively, nebulizer parts (except mask and tubing) may be disinfected by boiling in a clean pot of water for 5 minutes.
  • Hospitals and clinics can sterilize the PARI Reusable Nebulizer parts (except mask and tubing) by autoclaving (a maximum of 277° F or 136° C), follow autoclave manufacturer’s instructions.

Please refer to the Instructions For Use for more information.
*CONTROL III® is a registered trademark of Maril Products, Inc.

What is the difference between a Nebulizer and a Compressor?

The Compressor creates an airflow which travels to your nebulizer through tubing. The Nebulizer is your actual medicine cup. This is what turns your medication into a mist or aerosol.  For more information, please refer to the Understanding your Nebulizer Compressor System reference sheet.

What is the easycare cleaning aide?

The easycare cleaning aide is used to clean and unclog the microscopic holes in the eRapid Aerosol Head by reversing the flow of liquid (backwash). The easycare should be used no more than twice a week to maintain proper nebulization time. The Aerosol Head should not be used with easycare more than 25 times over its duration of use.1

1 Easycare Instructions for Use. 078D1022. Rev B 6/14

What is the eRapid Nebulizer System?

The eRapid Nebulizer System is a general-purpose nebulizer and part of the eFlow Technology platform of electronic nebulizers which use a vibrating membrane to generate aerosol. This membrane is perforated with several thousand laser-drilled holes. A piezoelectric actuator causes the membrane to vibrate 117,000 times per second (117 Kz) creating an alternating pressure field, which forces the medication through the holes and generates a fine, dense aerosol. The aerosol is suspended in a patented "valved aerosol chamber" until the patient inhales.

What medications are specifically approved by the FDA for use with the eRapid Nebulizer System?

Pulmozyme is FDA approved for use with the eRapid Nebulizer System. The eRapid Nebulizer System is a general-purpose nebulizer. Both the eRapid Nebulizer System and traditional jet nebulizers are intended for general use with currently approved nebulized medications at the discretion of the prescribing clinician.

What medications can be nebulized with the eRapid Nebulizer System?

The eRapid Nebulizer is a nebulizer for use in patients
for whom doctors have prescribed medication for nebulization1


1 eRapid Nebulizer System Instructions for Use. 178D1009. Rev B 10/12

What medications can be used with PARI Nebulizers?

PARI reusable nebulizers can be used with all inhalation medications approved for use with jet nebulizers and prescribed by a physician. PARI reusable nebulizers are the most widely used nebulizers by pharmaceutical companies in clinical trials for new medications compared to any other brand. Specifically, PARI nebulizers were used in the following clinical trials to prove safety and efficacy:

Pulmozyme® (Genentech), Pulmicort Respules® (AstraZeneca), TOBI® (Novartis), Perforomist®, DuoNeb®, and AccuNeb® (Dey), and Brovana® and Xopenex® (Sunovion) 

If you have questions, please consult your physician.

*All registered marks and trademarks belong to their respective companies.

When is a prescription required?

Due to Federal and State regulations and requirements, PARI does require a prescription for compressors, nebulizers, and other medical devices, prior to an order being billed and shipped in the US. Patient Connection will advise you if a prescription is needed. The prescription MUST come from your Medical Provider and can be faxed to 1.800.727.4112.

When using Bubbles the Fish II™ pediatric mask, should I leave my nebulizer cap on or off?

For the most effective medication delivery, PARI recommends that you keep your nebulizer cap on for the LC PLUS® and LC® Star reusable nebulizers, and in the closed position for the LC® Sprint reusable nebulizer.