News

Tuesday, 23. November 2010

Pilot study with MucoClear 6% in bronchiectasis: 12% of patients find improvements "life-changing“

Current study with 41 patients was presented during the annual congress of the European Respiratory Society

41 patients with bronchiectasis bronchiectasis
Bronchiectasis is an abnormal widening of one or more airways. Extra mucus is made in the abnormal airways which is prone to infection.
inhaled MucoClear 6% twice daily for two months. Lung function, sputum sputum
Sputum is mucus that is coughed up from the lower airways.
production and quality of life was monitored for any  
changes during this period of time. All study-participants’ overall condition had significantly improved with the use of nebulised 6% hypertonic saline – 12% found this improvement “life-changing”.

100% of the patients thought, that mucus was easier to cough up, approximately one half of participants were able to “get rid of”  increased amounts of sputum sputum
Sputum is mucus that is coughed up from the lower airways.
. Many patients on MucoClear 6%. therapy experienced improved oxygen saturation and lung function. In addition, responses from standardized questionnaires showed that patients quality of life had significantly ameliorated.

The study authors concluded that these results suggest that MucoClear 6% is a valuable option for patients with bronchiectasis bronchiectasis
Bronchiectasis is an abnormal widening of one or more airways. Extra mucus is made in the abnormal airways which is prone to infection.
– even if further controlled studies are recommended.

Bronchiectasis Bronchiectasis
Bronchiectasis is an abnormal widening of one or more airways. Extra mucus is made in the abnormal airways which is prone to infection.
patients suffer from pathological enlargement of the conducting airways (bronchi). Leading symptoms of this severe disease are coughing and large sputum sputum
Sputum is mucus that is coughed up from the lower airways.
volumes. Possible complications are pneumonia or hemoptysis. 

Diagramm - Pyne 2010 HS BE

12% of the bronchiectasis bronchiectasis
Bronchiectasis is an abnormal widening of one or more airways. Extra mucus is made in the abnormal airways which is prone to infection.
patients found the improvent of their overall condition under therapy with hypertonic saline "life changing".

Source: Pyne et al. (2010) Poster 4588 on the annual congress of the European Respiratory Society in Barcelona