Monday, 14. February 2011

Experience from daily routine of a pulmonologist: Nebulisers led to better disease control in his difficult cases of asthma or COPD

Dr. Marcus successfully switched adult patients with poorly controlled symptoms from metered dose or dry powder inhalers to nebulisers.

The US pulmonologist reported positive experience with nebuliser therapy. A systematic retrospective analysis of 25 of his “difficult” cases was published in the Journal of Applied Research. Patients were prescribed nebulised budesonide if their symptoms were poorly controlled on intensive therapy with metered dose or dry powder inhalers . This approach led to successful results: In many cases the number of acute exacerbations decreased and lung function improved.

To compare changes in the number of acute exacerbations, the year prior to switching to nebulised budesonide was used as a baseline for all patients compared to the year after switching to nebulised budesonide. Lung function had been measured three months prior to and after the switch respectively.

Study participants’ average age was 65 years old (31-84) with significantly more women than men. An adjustment of therapy had become necessary for all, patients as they had no relief from symptoms despite teaching correct inhaler technique and frequent monitoring of their compliance.

Source: Marcus (2009) Budesonide Inhalation Suspension in Adults with Poorly Controlled Asthma Asthma
Asthma is a common chronic inflammatory airway disease, characterized by variable and recurring symptoms, reversible airflow obstruction and bronchospasm.
or Chronic Obstructive Obstructive
Increased resistance in the airways that reduces the amount of air inhaled in each breath and the oxygen that reaches the pulmonary arteries
Pulmonary Disease. J Appl Research 9(1&2): 1-12