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Friday, 29. June 2012

Congress news in March/ April 2012

Hypertonic saline - also effective in bronchiectasis bronchiectasis
Bronchiectasis is an abnormal widening of one or more airways. Extra mucus is made in the abnormal airways which is prone to infection.
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Bronchiectasis Bronchiectasis
Bronchiectasis is an abnormal widening of one or more airways. Extra mucus is made in the abnormal airways which is prone to infection.
, permanent dilation of the bronchi and bronchioles as a result of muscle and elastic connective tissue destruction, occurs mainly in cystic fibrosis cystic fibrosis
Genetic disorder that affects most critically the lungs, leading to thick, viscous secretions.
patients. This disease also represents a very serious complication in 30-50% of patients with chronic obstructive obstructive
Increased resistance in the airways that reduces the amount of air inhaled in each breath and the oxygen that reaches the pulmonary arteries
pulmonary disease (COPD).

It is the physician's responsibility to choose an effective medication to suit the individual requirements of the patient.

To date, there are only a few evidence-based recommendations for the treatment of this disease.

At this year's congress of the German Society for Pneumology Pneumology
Pulmonology is the medical specialty dealing with disease involving the respiratory tract.
and Respiratory Medicine, various options were discussed [1,2].

In addition to anti-inflammatory and antibacterial medication, physiotherapy that improves drainage of secretions also play an important role.

And this point the inhalation of hypertonic saline (e.g. Mucoclear 6%) becomes involved, due to the proven positive effect on mucociliary clearance mucociliary clearance
Describes the self-clearing mechanism of the bronchi.
.

Initial studies in patients with COPD and bronchiectasis bronchiectasis
Bronchiectasis is an abnormal widening of one or more airways. Extra mucus is made in the abnormal airways which is prone to infection.
[3, 4] confirm the following effects of hypertonic saline

· Increased sputum sputum
Sputum is mucus that is coughed up from the lower airways.
production and ease of expectoration

· Improved lung function · Reduced annualized antibiotic usage

· Reduced number of exacerbations (worsening of the symptoms)

· Improved quality of life

Even though no official recommendations have yet been made, this information suggest that inhalation of hypertonic saline is an effective and cost efficient approach to successful therapy

 

1 Rademacher 2012; Kongress der deutschen Gesellschaft für Pneumologie Pneumologie
Lehre von den Erkrankungen der Atmungsorgane.

   und Beatmungsmedizin e.V.; Vortrag

2 Rademacher et al; Internist; 2010 Dec;51(12):1510-5

3 Kellet et al. Respir Med 2011; 105(12):1831

4 Nicolson et al. Am J Respir Crit Care Med 2010; 181:3183