Friday, 01. July 2016

Cochrane review confirms: PEP physiotherapy can help to reduce pulmonary flare ups in cystic fibrosis

Scientists from the Cochrane Collaboration concluded that positive expiratory pressure (PEP) are more effective than other airway clearance techniques in reducing pulmonary exacerbations in patients with cystic fibrosis (CF).


Chest physiotherapy is frequently used in patients with cystic fibrosis to improve ease of breathing by assisting in airway clearance. There are different techniques that can be taken. Given the widespead use of PEP devices, this review determines the evidence of their effect.

  • PEP devices decrease pulmonary exacerbations over the period of one year
  • Similar FEV1 values compared to other methods of airway clearance
  • Patients preferred PEP device

The researchers concluded that the patient’s preference for the used method is probably the most important factor because it directly affects the physiotherapeutic outcome.
The PARI PEP system combined with a PARI nebulizer offers a convenient and simple tool to make the most of this described effect

Source: McIlwaine M, Button B, Dwan K. Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis. Status Date New Search Stud Content Updat Conclus Chang Publ In. 2015;(6).