SUCCESSFUL INHALATION EVEN WITH SMALL INSPIRATORY FLOWS

Specific minimum inspiratory flows are needed in order to trigger dry powder inhalers. Scientific studies have shown that especially older people and infants have difficulty reaching these minimum thresholds1,2.
But with a nebuliser, patients can inhale even with very low inspiratory flows. In fact, slow inspiration is actually desirable, because it deposits less medication in the throat. This means that more active agent reaches the lungs.
It works best in conjunction with the PIF Control System – a breath sensory feedback system developed by PARI specially for this purpose.

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Science Links PIF Laube 1992

The effect of aerosol aerosol
An aerosol is a colloid of fine solid particles or liquid droplets, in air or another gas.
distribution on airway responsiveness to inhaled methacholine in patients with asthma asthma
Asthma is a common chronic inflammatory airway disease, characterized by variable and recurring symptoms, reversible airflow obstruction and bronchospasm.

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Science Links throat deposition Burnell 2007

Studies of the Human Oropharyngeal Airspaces Using Magnetic Resonance Imaging IV - The Oropharyngeal Retention Effect for Four Inhalation Delivery Systems

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Handling Errors Molimard 2003

Assessment of Handling of Inhaler Devices in Real Life: An Observational Study in 3811 Patients in Primary Care